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Weight Loss

The best diet while taking GLP-1 or GIP/GLP-1 medications

You'll be eating less, so every bite has to do more work. Protein first, vegetables next, water throughout — and a short list of foods that make the side effects worse.

3 min readReviewed by our Medical Practitioners

Someone cooking a real meal for themselves at home.

The short version

  1. Aim for roughly 20–30 grams of protein per meal, and eat the protein first.
  2. Fill the rest of the plate with vegetables, high-fiber carbohydrates and a small amount of healthy fat.
  3. Drink at least 64–80 ounces of water a day unless your provider says otherwise — it's the simplest fix for constipation, headaches and low energy.
  4. Three small meals plus a protein-rich snack usually sits better than three large ones.
  5. Fried, greasy, sugary and heavily processed foods are the ones most likely to make nausea and bloating worse.
  6. Don't skip meals when your appetite is low. A protein shake beats nothing.

GLP-1 and dual GIP/GLP-1 medications have transformed the way we approach weight management. These medications help reduce appetite, slow stomach emptying, improve blood sugar regulation, and make it easier to eat smaller portions. However, medication is only one part of the journey.

The foods you choose while taking GLP-1 or GIP/GLP-1 therapy can make a significant difference in your results. Eating nutrient-dense foods not only supports healthy weight loss but can also help minimize common side effects such as nausea, bloating, constipation, and fatigue.

Here are our top recommendations for building a healthy, sustainable eating plan while on GLP-1 therapy.

Focus on protein first

Because you'll likely be eating smaller portions, every bite counts. Protein should be the foundation of most meals. Adequate protein helps:

  • Preserve lean muscle during weight loss
  • Keep you feeling full longer
  • Support metabolism
  • Promote recovery after exercise

Aim for approximately 20–30 grams of protein per meal, depending on your individual needs. Great protein choices include:

  • Chicken or turkey
  • Fish and seafood
  • Eggs
  • Greek yogurt
  • Cottage cheese
  • Tofu or tempeh
  • Lean beef
  • Protein shakes when needed

Start each meal with your protein before moving on to other foods.

Eat plenty of vegetables

Vegetables provide fiber, vitamins, minerals, and antioxidants while adding volume without excessive calories. Choose a variety of colorful vegetables such as:

  • Broccoli
  • Spinach
  • Asparagus
  • Bell peppers
  • Green beans
  • Brussels sprouts
  • Cauliflower
  • Zucchini
  • Cucumbers
  • Leafy greens

Cooked vegetables may be easier to tolerate if you're experiencing nausea early in treatment.

Include healthy fats

Healthy fats support hormone production, brain health, and satisfaction after meals. Good sources include:

  • Avocados
  • Olive oil
  • Nuts
  • Seeds
  • Natural nut butters
  • Fatty fish like salmon

A small amount goes a long way since fats digest more slowly.

Choose high-fiber carbohydrates

Carbohydrates aren't the enemy—they're an important source of energy when you choose wisely. Focus on:

  • Oatmeal
  • Brown rice
  • Quinoa
  • Sweet potatoes
  • Beans
  • Lentils
  • Fresh fruit
  • Whole grain bread or wraps

Fiber supports digestive health and may help reduce constipation, a common side effect of GLP-1 medications. Increase fiber gradually and drink plenty of water.

Stay well hydrated

Many people unintentionally drink less water because they feel full more quickly. Aim for at least 64–80 ounces of water daily, unless your provider recommends otherwise. Hydration helps:

  • Reduce constipation
  • Improve energy
  • Support metabolism
  • Prevent dehydration
  • Minimize headaches

If plain water is difficult to drink, try:

  • Electrolyte beverages with low or no added sugar
  • Herbal tea
  • Sparkling water
  • Water infused with lemon, cucumber, or berries

Eat smaller meals more frequently

GLP-1 medications slow stomach emptying, making large meals uncomfortable. Instead of three large meals, many patients do better with:

  • Three small meals
  • One or two protein-rich snacks if needed

Eat slowly, chew thoroughly, and stop eating as soon as you feel comfortably satisfied—not overly full.

Foods to limit

While no foods are completely off-limits, some may worsen side effects or slow your progress. Try limiting:

  • Fried foods
  • Greasy or high-fat meals
  • Sugary desserts
  • Candy
  • Soda
  • Highly processed snacks
  • Large portions
  • Heavy cream-based dishes
  • Excess alcohol

These foods may increase nausea, bloating, heartburn, or stomach discomfort.

Don't skip meals

Even if your appetite is low, it's important to nourish your body. Skipping meals can lead to:

  • Fatigue
  • Low energy
  • Muscle loss
  • Poor nutrition
  • Difficulty meeting protein goals

Lifestyle habits that support success

Medication works best when paired with healthy habits. We encourage patients to:

  • Strength train 2–3 times per week to preserve muscle.
  • Walk or engage in regular physical activity.
  • Get 7–9 hours of sleep each night.
  • Manage stress through mindfulness, yoga, or relaxation techniques.
  • Keep regular follow-up appointments with their healthcare provider.

Small, consistent changes often lead to the most sustainable results.

The bottom line

GLP-1 and GIP/GLP-1 medications are powerful tools, but nutrition remains a cornerstone of long-term success. Prioritizing protein, vegetables, fiber, hydration, and balanced meals can help maximize weight loss, preserve muscle, reduce side effects, and support overall health.

Remember, every person's nutritional needs are unique. Working with your healthcare provider ensures your treatment plan is tailored to your goals, lifestyle, and medical history.

This article is general health information, not medical advice, and it isn’t a substitute for a consultation. Whether any therapy is appropriate for you depends on your history, your medications and your goals — which is what your Medical Practitioner reviews before anything is prescribed.

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